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. 2022 Feb 19;118:119–125. doi: 10.1016/j.ijid.2022.02.039

Table 2.

Characteristics of the patients after weighted by inverse probability of censoring/discharge at the beginning of the observation

Regimen 1 (treated with remdesivir) Regimen 2 (treated without remdesivir) Standardized mean difference
Number 9,183 9,175
Age (years) 50.3 (21.5) 50.2 (21.5) 0.004
Male 52.3% 52.5% 0.002
Cardiovascular disease 4.1% 4.1% <0.001
Respiratory disease 2.0% 2.0% 0.003
Diabetes mellitus 10.4% 10.4% <0.001
Severe renal disease or dialysis 1.3% 1.3% 0.002
Hypertension 21.3% 21.1% 0.006
Obesity 6.5% 6.5% 0.003
Charlson Comorbidity Index 0.45 (0.95) 0.45 (0.95) 0.001
NEWS at Day 1 1.02 (1.17) 1.01 (1.17) 0.002
NEWS at Day 4 1.18 (1.34) 1.18 (1.34) 0.001
NEWS at Day 8 1.28 (1.58) 1.28 (1.57) 0.001
NEWS at Day 15 1.62 (2.01) 1.63 (2.02) 0.004
NEWS at Day 22 1.88 (2.39) 1.87 (2.38) 0.005
NEWS at Day 29 10.11 (1.92) 10.13 [1.96] 0.011
Fatal cases 1.7% 1.7% <0.001
Oxygen administration during hospitalization* 9.4% 9.4% 0.001
IMV/ECMO during hospitalization 0.5% 0.5% 0.001
Days from symptom onset to hospitalization 2.62 (1.60) 2.62 (1.60) <0.001
Use of systemic steroids 9.6% 9.5% 0.005
Use of favipiravir 9.4% 9.4% 0.002
Use of tocilizumab 0.4% 0.4% <0.001
Use of baricitinib 0 (0%) 0 (0%) <0.001

Regimen 1: treated with remdesivir.

Regimen 2: treated without remdesivir.

Continuous variables are presented mean (standard deviation). Categorical variables are presented in percentage.

IMV/ECMO = invasive mechanical ventilation/extracorporeal membrane oxygenation; NEWS = national early warning score.