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. 2022 Feb 19;41:68. doi: 10.1186/s13046-022-02272-x

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© The Author(s) 2022

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 15 — A Schematic illustration of the tumor-associated-macrophage-membrane-coated up conversion nanoparticles for improved photodynamic immunotherapy. B-J In vivo antitumor therapeutic effects. B Schematic illustration of 4 T1 tumor model establishment and the therapeutic regimen. C Tumor growth curves for primary tumor and distant tumor. D Tumor weight for primary tumor. E Tumor weight for distant tumor. F Histological analysis of H&E staining for primary and distant tumor. G Photographs show representative external views of lung with the histological analysis of H&E staining. Arrows indicate focal tumor nodules on lung surfaces. Scale bar = 100 μm. (H, I) Graphs show the quantification of metastatic foci (H) and lesion area (I) in the different treatment groups from part f. J The survival curve of tumor-bearing mice calculated by Kaplan−Meier estimate. Data are means ± SD. *P < 0.05; **P < 0.01. NS, no significance. n = 6/group [203]