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. 2022 Feb 18;53:12. doi: 10.1186/s13567-022-01029-w

Table 10.

T cell epitope content comparison (EpiCC) analysis

Treatment Group (T) and description EpiCC scores Percent coverage % Improvement of homologous vs heterologous coverage a
Vaccine Challenge PCV2a ORF2 b PCV2b ORF2 c PCV2a ORF2 b PCV2b ORF2 c
T02 homologous treatment cPCV2a PCV2a 10.42 d 7.51 100.00 72.05 36.46
T04 heterologous treatment cPCV2a PCV2b 7.51 10.25 d 73.28 100.00

a The percent improvement of homologous (cPCV2a vaccine, PCV2a challenge) versus heterologous (cPCV2a vaccine, PCV2b challenge) coverage (|(heterologous-homologous)|/heterologous * 100%) representing the situation in Study A.

b Situation tested in studies A and B.

c Situation tested in study C.

d Represents baseline where the challenge strain is identical to the vaccine strain.