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Mendelian randomization model of leukocyte TL and risk of JIA and JIA-associated iridocyclitis. The study design is under the assumption that genetic variants are directly associated with TL, but not indirectly with TL and not directly with confounders, that is, the instrumental variables influence JIA and JIA-associated iridocyclitis only directly through TL.
Abbreviations: SNP, single-nucleotide polymorphism; TL, telomere length; JIA, juvenile idiopathic arthritis.
