Table 3.
Permeation Parameters Calculated from the TR146 Cell Permeation Study
| Formulation | Js (ng·cm−2·h−1) | Kp (cm·h−1) × 10−3 | ER |
|---|---|---|---|
| sCT | 11.726 ± 2.527 | 0.147 ± 0.032 | 1.0 |
| Control liposomes | 35.649 ± 2.906 | 0.446 ± 0.036*** | 3.0 |
| Penetratin-conjugated liposomes | 68.416 ± 10.093 | 0.855 ± 0.126*** ## | 5.8 |
Notes: Data are expressed as mean ± SD (n = 3). ***p<0.001 vs sCT, ##p<0.01 vs Control liposomes.
Abbreviations: Js, Flux; Kp, Permeability coefficient; ER, Enhancement ratio.