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Permeation Parameters Calculated from the Buccal Tissue Permeation Study
| Formulation | Js (ng·cm−2·h−1) | Kp (cm·h−1) × 10−3 | ER |
|---|---|---|---|
| sCT | 0.173 ± 0.018 | 0.004 ± 0.000 | 1.0 |
| Control liposomes | 6.384 ± 0.718 | 0.160 ± 0.018*** | 37.0 |
| Penetratin-conjugated liposomes | 15.802 ± 1.263 | 0.395 ± 0.032*** ### | 91.5 |
Notes: Data are expressed as mean ± SD (n = 3). ***p<0.001 vs sCT, ###p<0.001 vs Control liposomes.
Abbreviations: Js, Flux; Kp, Permeability coefficient; ER, Enhancement ratio.
