Table 1.
Relationship Between NRI-HGS Score and All-Cause Mortality in Patients with Cancer Cachexia
| NRI-HGS Score | Model 1 HR (95% CI) |
p value | Adjusted Model 2 HR (95% CI) |
p value | Adjusted Model 3 HR (95% CI) |
p value |
|---|---|---|---|---|---|---|
| Training cohort | ||||||
| Normal | Ref | Ref | Ref | |||
| Mild | 1.652 (1.334–2.046) | <0.001 | 1.4 (1.126–1.742) | 0.003 | 1.324 (1.059–1.656) | 0.014 |
| Moderate | 2.746 (2.23–3.381) | <0.001 | 2.455 (1.957–3.08) | <0.001 | 2.176 (1.718–2.756) | <0.001 |
| Severe | 4.426 (3.481–5.628) | <0.001 | 3.374 (2.546–4.473) | <0.001 | 2.745 (2.023–3.725) | <0.001 |
| Validation cohort | ||||||
| Normal | Ref | Ref | Ref | |||
| Mild | 2.397 (1.648–3.486) | <0.001 | 2.018 (1.379–2.954) | <0.001 | 1.826 (1.233–2.705) | 0.003 |
| Moderate | 3.378 (2.318–4.921) | <0.001 | 2.831 (1.897–4.225) | <0.001 | 2.298 (1.500–3.52) | <0.001 |
| Severe | 6.064 (4.008–9.173) | <0.001 | 4.199 (2.632–6.698) | <0.001 | 2.855 (1.684–4.84) | <0.001 |
Notes: Model 1: No adjusted. Model 2: Adjusted for age, BMI, TNM stage, surgery, radiotherapy, chemotherapy, hypertension, diabetes, smoke, alcohol, family history, weight loss. Model 3: Adjusted for age, BMI, TNM stage, surgery, radiotherapy, chemotherapy, hypertension, diabetes, smoke, alcohol, family history, weight loss, WBC, neutrophil, lymphocyte, platelet, RBC, hemoglobin.