Table 2.
Nomogram Score | Model 1 HR (95% CI) |
p value | Adjusted Model 2 HR (95% CI) |
p value | Adjusted Model 3 HR (95% CI) |
p value |
---|---|---|---|---|---|---|
Training cohort | ||||||
Normal | Ref | Ref | Ref | |||
Mild | 2.496 (1.857–3.356) | <0.001 | 1.945 4.5(1.299–2.91) | 0.001 | 1.69 (1.127–2.533) | 0.011 |
Moderate | 6.051 (4.596–7.965) | <0.001 | 3.716 (2.293–6.02) | <0.001 | 2.874 (1.759–4.695) | 0.001 |
Severe | 13.734 (10.504–17.956) | <0.001 | 6.974 (4.077–11.93) | <0.001 | 4.595 (2.639–7.999) | <0.001 |
Validation cohort | ||||||
Normal | Ref | Ref | Ref | |||
Mild | 2.91 (1.669–5.074) | <0.001 | 2.628 (1.279–5.403) | 0.009 | 2.173 (1.035–4.559) | 0.040 |
Moderate | 5.746 (3.388–9.744) | <0.001 | 4.011 (1.782–9.028) | 0.001 | 2.778 (1.198–6.44) | 0.017 |
Severe | 13.714 (8.196–22.948) | <0.001 | 7.587 (3.22–17.876) | <0.001 | 4.626 (1.866–11.472) | 0.001 |
Notes: Model 1: No adjusted. Model 2: Adjusted for age, BMI, TNM stage, surgery, radiotherapy, chemotherapy, hypertension, diabetes, smoke, alcohol, family history, weight loss. Model 3: Adjusted for age, BMI, TNM stage, surgery, radiotherapy, chemotherapy, hypertension, diabetes, smoke, alcohol, family history, weight loss, WBC, neutrophil, lymphocyte, platelet, RBC, hemoglobin.