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. 2022 Feb 15;15:1005–1015. doi: 10.2147/JIR.S352250

Table 2.

Relationship Between Nomogram and All-Cause Mortality in Patients with Cancer Cachexia

Nomogram Score Model 1
HR (95% CI)
p value Adjusted Model 2
HR (95% CI)
p value Adjusted Model 3
HR (95% CI)
p value
Training cohort
Normal Ref Ref Ref
Mild 2.496 (1.857–3.356) <0.001 1.945 4.5(1.299–2.91) 0.001 1.69 (1.127–2.533) 0.011
Moderate 6.051 (4.596–7.965) <0.001 3.716 (2.293–6.02) <0.001 2.874 (1.759–4.695) 0.001
Severe 13.734 (10.504–17.956) <0.001 6.974 (4.077–11.93) <0.001 4.595 (2.639–7.999) <0.001
Validation cohort
Normal Ref Ref Ref
Mild 2.91 (1.669–5.074) <0.001 2.628 (1.279–5.403) 0.009 2.173 (1.035–4.559) 0.040
Moderate 5.746 (3.388–9.744) <0.001 4.011 (1.782–9.028) 0.001 2.778 (1.198–6.44) 0.017
Severe 13.714 (8.196–22.948) <0.001 7.587 (3.22–17.876) <0.001 4.626 (1.866–11.472) 0.001

Notes: Model 1: No adjusted. Model 2: Adjusted for age, BMI, TNM stage, surgery, radiotherapy, chemotherapy, hypertension, diabetes, smoke, alcohol, family history, weight loss. Model 3: Adjusted for age, BMI, TNM stage, surgery, radiotherapy, chemotherapy, hypertension, diabetes, smoke, alcohol, family history, weight loss, WBC, neutrophil, lymphocyte, platelet, RBC, hemoglobin.