Fig. 3.

ROC analyses of IgM-free AIM, AFP, and DCP for all cancer stages. The sensitivity and specificity of the markers were determined to discriminate the patients with HCC from those without HCC. a–d Include all cancer stages of NASH-HCC, HBV-HCC, HCV-HCC, and all the patients, respectively. IgM-free AIM showed the highest AUROC for each disease group and all the patients. AFP alpha-fetoprotein, AIM apoptosis inhibitor of macrophage, DCP des-γ-carboxy prothrombin, HBV hepatitis B virus, HCC hepatocellular carcinoma, HCV hepatitis C virus, NASH non-alcoholic steatohepatitis, ROC receiver operating characteristic, AUROC area under the receiver operating characteristic