Table 2.
Comparison of viscoelastic parameters, labs, and incidence of VTE between patients who did and did not demonstrate fibrinolysis shutdown on ROTEM testing
| Fibrinolysis shutdown | Non-fibrinolysis shutdown | P | |
|---|---|---|---|
| n | 11 (44%) | 14 (56%) | |
| d-dimer level (ng/mL) | 5,215 (2,21, 6,925) | 1,431 (1,159, 1,429) | 0.1080 |
| Platelet count (103/mL) | 288 (217, 394) | 294 (231, 387) | 0.9568 |
| EXTEM CT (s) | 90 (63, 107) | 80 (66, 93) | 0.9567 |
| EXTEM MCF (mm) | 78 (72, 81) | 76.5 (74, 79) | 0.9783 |
| FIBTEM MCF (mm) | 45 (39, 52) | 43 (41, 50) | 0.9136 |
| EXTEM ML (%) | 1.0, (1.0, 2.0) | 4.5 (4.0, 6.0) | 0.0003 |
| Patients with VTE | 8 (73%) | 1 (7%) | 0.0021 |
P values based upon Fisher exact test for categorical variables and Wilcoxon rank sum test for continuous variables. Data presented as median (1st quartile, 3rd quartile) or number (%).The d-dimer and platelet count values were those obtained immediately preceding the ROTEM by up to 24 h.
CT indicates clot time; MCF maximum clot firmness; ML, maximum lysis; VTE, venous thromboembolic.