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. 2022 Feb 19;10:8. doi: 10.1186/s40364-022-00353-9

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© The Author(s) 2022

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 5 — FAM83A overexpression induced metabolic pathway activation in primary epithelial cells. A Ingenuity pathway analysis (IPA) revealed the canonical pathways linked with the genes differentially expressed between FAM83A-overexpressing and control cells. Downregulated genes are in green and upregulated genes are in red. B Molecular networks linking the differentially expressed genes were obtained using IPA. Upregulated genes are shown in red while downregulated genes are in green and connecting molecules are white. The three networks shown in the figure include: Cancer and endocrine system disorders (left); Cancer and cell morphology (center); and Carbohydrate metabolism (right)