FIGURE 6.

PTGS2 antisense NF‐κB1 complex‐mediated expression regulator RNA (PACERR) is necessary for the regulation of prostaglandin‐endoperoxide synthase 2 (PTGS2) in tumour‐associated macrophages (TAMs). (A,B) The protein expression of PTGS2 were not significantly changed after CCCTC‐binding factor (CTCF) overexpression in THP‐1‐sh1PACERR (A) derived TAMs and THP‐1‐sh2 PACERR (B) derived TAMs. (C) and (D) Invasion and capacity and migration capacity of PANC‐1 cells co‐cultured with THP‐1‐derived TAMs after CTCF overexpression in THP‐1‐sh1PACERR (C) derived TAMs and THP‐1‐sh2 PACERR (D) derived TAMs. “ns” means not statistically significant. Image is representative of three independent experiments