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. 2022 Feb 7;13:820685. doi: 10.3389/fimmu.2022.820685

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Copyright © 2022 Wang, Deng, Sun, Zhao, Li, Yang, Yuan, Liu, Qian, Zhou and Kang

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Inflammatory cytokine levels and proportions of Th cell subpopulations in peripheral blood of rats in each group. (A–I) Inflammatory cytokine levels in serum of rats in each group (*compared with the model group); (J) circle gating strategy for flow cytometry analysis of peripheral blood Th cell proportions; (K, L, N, O) flow analysis of the proportions of Th1, Th2, Th17, and Treg cells in peripheral blood as a percentage of CD4⁺ T cells; (M) ratio of Th1/Th2 in peripheral blood of rats in each group; (P) ratio of Th17/Treg in peripheral blood of rats in each group. n=5, *p<0.05, **p<0.01, ***p<0.001.