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. Author manuscript; available in PMC: 2023 Feb 1.
Published in final edited form as: Alcohol Clin Exp Res. 2021 Dec 29;46(2):221–231. doi: 10.1111/acer.14760

Figure 4: Upregulated EV-miRNA associated with heightened inflammatory response in PBMC.

Figure 4:

A) Experimental design for miRNA candidate selection and electroporation created using Biorender.com. B,C) PBMC from control macaques were transfected with miRNA mimics and further stimulated with PMA/ionomycin. The production of TNFα (D) and IL-6 (E) was measured from supernatants by ELISA. P-value significance is denoted by *=<0.05, **=<0.01, ***=<0.001.