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. Author manuscript; available in PMC: 2023 Apr 1.
Published in final edited form as: Exp Neurol. 2021 Dec 28;350:113963. doi: 10.1016/j.expneurol.2021.113963

Table 1 –

Gait Analysis Day 7

Main effect of Interaction
Parameter Sham Saline Sham Ketamine ABS Saline ABS Ketamine ABS Ketamine
Stride length Forepaw 3.47 ± 0.09 3.86 ± 0.06 3.55 ± 0.06 4.18 ± 0.15 n.s. F(1,94) = 26.18, p=0.001 n.s.
Hindpaw 3.69 ± 0.07 3.88 ± 0.07 3.50 ± 0.06 4.06 ± 0.07 n.s. F(1,94) = 21.61, p=0.001 F(1,94) = 5.04, p=0.027
Stride Frequency Forepaw 2.82 ± 0.17 2.38 ± 0.04 2.59 ± 0.06 2.27 ± 0.15 n.s. F(1,94) = 17.6, p=0.001 n.s.
Hindpaw 2.54±0.05 2.38 ± 0.06 2.66 ± 0.07 2.27 ± 0.04 n.s. F(1,94) = 21.26, p=0.001 n.s.
Stride Duration Forepaw 0.38 ± 0.01 0.43 ± 0.01 0.39 ± 0.01 0.46 ± 0.02 n.s. F(1,94) = 26.31, p=0.001 n.s.
Hindpaw 0.41 ± 0.01 0.43 ± 0.01 0.39 ± 0.01 0.45 ± 0.01 n.s. F(1,94) = 21.67, p=0.001 F(1,94) = 4.941, p=0.028
Stance Duration Forepaw 0.27 ± 0.01 0.29 ± 0.01 0.29 ± 0.01 0.35 ± 0.02 F(1,94) = 10.25, p=0.019 F(1,94) = 21.6, p=0.001 n.s.
Hindpaw 0.32 ± 0.01 0.33 ± 0.01 0.29 ± 0.01 0.35 ± 0.01 n.s. F(1,94) = 18.62, p=0.001 F(1,94) = 4.122, p=0.045
Propel Duration Forepaw 0.15 ± 0.01 0.17 ± 0.01 0.16 ± 0.01 0.19 ± 0.01 n.s. F(1,94) = 15.15, p=0.002 n.s.
Hindpaw 0.25 ± 0.01 0.25 ± 0.01 0.23 ± 0.01 0.25 ± 0.01 n.s. n.s. n.s.
Brake Duration Forepaw 0.12 ± 0.01 0.12 ± 0.004 0.13 ± 0.01 0.15 ± 0.01 F(1,94) = 7.50, p=0.007 F(1,94) = 6.08, p=0.015 n.s.
Hindpaw 0.07 ± 0.01 0.09 ± 0.01 0.06 ± 0.004 0.09 ± 0.01 n.s. F(1,94) = 22.45, p=0.001 n.s.
Swing Duration Forepaw 0.12 ± 0.004 0.13 ± 0.004 0.10 ± 0.003 0.12 ± 0.004 F (1,94) =8.01, p=0.057 F (1,94) = 12.81, p=0.005 n.s.
Hindpaw 0.09 ± 0.002 0.09 ± 0.001 0.09 ± 0.002 0.10 ± 0.004 n.s. F (1,94) = 7.264, p=0.008 n.s.
Stance/Swing Forepaw 2.43 ± 0.09 2.40 ± 0.08 2.9 ± 0.15 3.1 ± 0.15 F(1,94) = 19.46, p=0.001 n.s. n.s.
Hindpaw 3.47 ± 0.09 3.47 ± 0.09 3.31 ± 0.10 3.48 ± 0.12 n.s. n.s. n.s.
MAX dA/dT (cm^2/s) Forepaw 20.7 ± 0.88 24.3 ± 0.97 24.5 ± 1.10 29.7 ± 1.80 F(1,94) = 12.41, p=0.001 F(1,94) = 14, p=0.001 n.s.
Hindpaw 53.5 ± 2.16 59.11 ± 2.23 51.35 ± 2.31 51.68 ± 2.39 F (1,94) = 4.445, p=0.036 n.s n.s
Paw Placement Position 0.59 ± 0.04 0.45 ± 0.06 0.37 ± 0.05 0.23 ± 0.07 F (1,94) = 10, p=0.002 F (1,94) = 7.964, p=0.006 n.s.
Overlap Distance 2.52 ± 0.14 1.67 ± 0.16 1.5 ± 0.14 0.97 ± 0.16 F (1,94) = 36.05, p=0.001 F (1,94) = 31.22, p=0.001 n.s.
Gait Symmetry 1.10 ± 0.04 0.99 ± 0.01 0.98 ± 0.01 0.99 ± 0.02 F (1,94) = 5.396, p=0.032 n.s. F (1,94) = 4.753, p=0.022