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. Author manuscript; available in PMC: 2023 Apr 1.
Published in final edited form as: Exp Neurol. 2021 Dec 28;350:113963. doi: 10.1016/j.expneurol.2021.113963

Table 2 –

Gait Analysis Day 35

Main effect of Interaction
Parameter Sham Saline Sham Ketamine ABS Saline ABS Ketamine ABS Ketamine
Stride length Forepaw 3.66 ± 0.11 3.38 ± 0.11 3.30 ± 0.16 3.67 ± 0.12 n.s. n.s n.s.
Hindpaw 3.6 ± 0.13 3.48 ± 0.10 3.6 ± 0.10 3.41 ± 0.12 n.s. n.s. n.s.
Stride Frequency Forepaw 2.52 ± 0.08 2.7 ± 0.09 2.75 ± 0.12 2.94 ± 0.19 n.s. n.s n.s.
Hindpaw 2.7 ± 0.19 2.7 ± 0.08 2.58 ± 0.07 2.73 ± 0.1 n.s. n.s n.s.
Stride Duration Forepaw 0.38 ± 0.01 0.43 ± 0.01 0.39 ± 0.01 0.46 ± 0.02 n.s. n.s n.s.
Hindpaw 0.41 ± 0.01 0.43 ± 0.01 0.39 ± 0.01 0.45 ± 0.01 n.s. n.s n.s
Stance Duration Forepaw 0.27 ± 0.01 0.30 ± 0.01 0.29 ± 0.01 0.35 ± 0.02 n.s. n.s. n.s.
Hindpaw 0.32 ± 0.01 0.33 ± 0.01 0.30 ± 0.01 0.35 ± 0.01 n.s. n.s n.s.
Propel Duration Forepaw 0.15 ± 0.01 0.17 ± 0.01 0.16 ± 0.01 0.19 ± 0.01 n.s. F(1,92) = 5.39, p=0.022 n.s.
Hindpaw 0.25 ± 0.01 0.25 ± 0.01 0.23 ± 0.01 0.25 ± 0.01 n.s. F(1,92) = 4.72, p=0.033 n.s.
Brake Duration Forepaw 0.12 ± 0.01 0.12 ± 0.004 0.13 ± 0.01 0.15 ± 0.01 n.s. n.s n.s.
Hindpaw 0.07 ± 0.01 0.09 ± 0.01 0.06 ± 0.004 0.09 ± 0.01 n.s. F(1,92) = 6.02, p=0.016 n.s.
Swing Duration Forepaw 0.12 ± 0.004 0.13 ± 0.004 0.10 ± 0.003 0.12 ± 0.004 n.s. n.s. n.s.
Hindpaw 0.09 ± 0.002 0.09 ± 0.001 0.09 ± 0.002 0.10 ± 0.004 n.s. n.s n.s.
Stance/Swing Forepaw 2.43 ± 0.09 2.40 ± 0.08 2.9 ± 0.15 3.1 ± 0.15 n.s. n.s. n.s.
Hindpaw 3.47 ± 0.09 3.47 ± 0.09 3.31 ± 0.10 3.48 ± 0.12 n.s. n.s. n.s.
MAX dA/dT (cm^2/s) Forepaw 20.7 ± 0.88 24.9 ± 0.97 24.2 ± 1.10 29.7 ± 1.80 n.s n.s n.s.
Hindpaw 55.5 ± 2.16 59.11 ± 2.23 51.35 ± 2.31 59.67 ± 2.39 n.s n.s n.s
Paw Placement Position 0.49 ± 0.56 0.43 ± 0.08 0.43 ± 0.06 0.33 ± 0.07 n.s n.s. n.s.
Overlap Distance 1.64 ± 0.56 1.60 ± 0.19 1.3 ± 0.3 1.05 ± 0.2 F (1,92) = 4.14, p=0.045 n.s. n.s.
Gait Symmetry 0.97 ± 0.03 0.99 ± 0.01 1.07 ± 0.05 1.19 ± 0.15 F (1,92) = 5.53, p=0.029 n.s. n.s.