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. Author manuscript; available in PMC: 2023 May 1.
Published in final edited form as: Autism. 2021 Aug 21;26(4):975–987. doi: 10.1177/13623613211039662

Table 3.

Adjusted Regressions, ASD Only, ASD+ID, ID Only, and MHC as Predictors for Risk Factors or Comorbidities, Odds Ratios [99% Confidence Intervals]

Population ASD/ID Random Sample (no ASD/ID)

ASD Only ASD+ID ID Only MHC

OR [99% CI] OR [99% CI] OR [99% CI] OR [99% CI]

Risk Factor

1 Living in primary care shortage areas, high 0.87 [0.83,0.91] 0.87 [0.83,0.91] 0.99 [0.97,1.01]a 1.02 [1.00,1.03]a
2 Living in a residential facility 8.87 [8.29,9.50] 58.73 [55.36,62.31] 32.25 [31.05,33.49] 2.77 [2.67,2.88]
3 Receiving services in the home regularly from outside caregivers 3.92 [3.71,4.14] 6.57 [6.28,6.87] 7.02 [6.82,7.22] 2.53 [2.47,2.60]
4 Had hospitalization (psychiatric or inpatient) >=30 days over 5 years 3.28 [2.77,3.90] 2.79 [2.41,3.23] 3.85 [3.50,4.24] 4.10 [3.78,4.46]
5 Avoidable hospitalizations
6 Any 2.34 [2.25,2.42] 4.89 [4.73,5.05] 3.51 [3.45,3.57] 3.61 [3.56,3.65]
7  COPD, chronic bronchitis, asthma 1.57 [1.50,1.64] 1.41 [1.36,1.46] 1.74 [1.71,1.78] 3.26 [3.21,3.31]
8  Congestive heart failure 0.98 [0.87,1.09]a 0.82 [0.75,0.90] 1.32 [1.27,1.37] 1.91 [1.84,1.98]
9  Constipation, fecal impaction, and obstipation 4.09 [3.78,4.42] 9.59 [9.01,10.20] 5.46 [5.24,5.70] 3.15 [3.05,3.25]
10  Dehydration, volume depletion including acute renal failure and hyponatremia 1.82 [1.65,1.99] 2.46 [2.30,2.64] 2.39 [2.30,2.49] 2.95 [2.85,3.06]
11  Hypertension and hypotension 1.86 [1.76,1.95] 1.85 [1.77,1.92] 1.67 [1.64,1.71] 2.33 [2.29,2.37]
12  Poor glycemic control 1.72 [1.61,1.84] 1.46 [1.38,1.54] 1.35 [1.32,1.39] 1.75 [1.71,1.79]
13  Seizures 3.81 [3.59,4.05] 10.34 [9.87,10.84] 9.17 [8.87,9.48] 3.41 [3.30,3.51]
14  Urinary tract infection 1.76 [1.66,1.86] 3.07 [2.94,3.21] 2.85 [2.77,2.92] 2.56 [2.52,2.60]
15  Weight loss (failure to thrive) and nutritional deficiencies 3.89 [3.51,4.31] 9.57 [8.85,10.35] 6.44 [6.10,6.81] 3.25 [3.10,3.40]

Comorbidities

16 Any 1.50 [1.44,1.56] 1.52 [1.47,1.57] 1.55 [1.52,1.57] 2.56 [2.53,2.60]
17 Cancer 1.54 [1.42,1.67] 1.59 [1.49,1.69] 1.44 [1.39,1.49] 2.03 [1.97,2.08]
18 Chronic kidney disease 0.89 [0.82,0.96] 0.95 [0.89,1.01]a 1.16 [1.12,1.19] 1.87 [1.82,1.92]
19 Chronic lung disease 1.37 [1.27,1.46] 0.96 [0.90,1.02]a 1.61 [1.56,1.65] 3.89 [3.81,3.98]
20 Diabetes 1.48 [1.40,1.56] 1.26 [1.21,1.32] 1.25 [1.23,1.28] 1.64 [1.61,1.67]
21 Immunocompromised 1.17 [0.88,1.54]a 0.97 [0.76,1.22]a 0.86 [0.75,0.98] 2.00 [1.79,2.23]
22 Previous Organ Transplant Recipient 0.29 [0.23,0.38] 0.16 [0.13,0.21] 0.27 [0.24,0.29] 0.76 [0.69,0.83]
23 Serious Heart Conditions 0.98 [0.89,1.09]a 0.80 [0.74,0.87] 1.30 [1.25,1.34] 1.95 [1.89,2.02]
24 Severe Obesity 2.37 [2.23,2.52] 2.16 [2.05,2.28] 1.89 [1.83,1.95] 2.16 [2.11,2.21]
25 Sickle Cell Disease 0.57 [0.37,0.90] 0.25 [0.16,0.39] 0.48 [0.40,0.58] 1.50 [1.27,1.76]

Notes: ASD=autism spectrum disorder, ID=intellectual disability, MHC=mental health conditions. Regressions control for age group, sex, race, ethnicity, eligibility type, insurance type, Medicare dual eligibility and state; comparison is to the random sample with no ID, ASD, or MHC.

a

p-value is not less than 0.01 (for all other estimates, p<0.01)