TABLE 3.
Analysis of genotypes for rs777591 of USP34 among nonsmokers and smokers.
| SNV | Model | Genotype | Nonsmokers | Smokers | Heterogeneity test | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Case | Control | OR (95%CI) a | P a | Case | Control | OR (95%CI) a | P a | χ2 | P | |||
| rs777591 of USP34 | Genotype | A/A | 31 (8.33%) | 67 (14.41%) | 0.511 (0.3102–0.8417) | .0084 | 14 (11.38%) | 9 (13.04%) | 0.8972 (0.3212–2.506) | 0.8359 | 0.93 | .3340 |
| G/A | 183 (49.19%) | 217 (46.67%) | 0.9889 (0.7282–1.343) | .9428 | 50 (40.65%) | 32 (46.38%) | 0.7609 (0.388–1.492) | 0.4263 | 0.48 | .487 | ||
| G/G | 158 (42.48%) | 181 (38.92%) | 1 | — | 59 (47.97%) | 28 (40.58%) | 1 | — | — | — | ||
| Dominant | A/A, G/A | 214 (57.53%) | 284 (61.08%) | 0.8723 (0.6514–1.168) | .3591 | 64 (52.03%) | 41 (59.42%) | 0.7887 (0.4178–1.489) | 0.4642 | 0.08 | .775 | |
| G/G | 158 (42.47%) | 181 (38.92%) | 1 | — | 59 (47.97%) | 28 (40.58%) | 1 | — | — | — | ||
| Recessive | A/A | 31 (8.33%) | 67 (14.41%) | 0.514 (0.3208–0.8237) | .0057 | 14 (11.38%) | 9 (13.04%) | 1.026 (0.3883–2.709) | 0.9592 | 1.57 | .210 | |
| G/G, G/A | 341 (91.67%) | 398 (85.59%) | 1 | — | 109 (88.62%) | 60 (86.96%) | 1 | — | — | — | ||
| Allele | A | 245 (32.93%) | 351 (37.74%) | 0.8053 (0.6507–0.9964) | .0463 | 78 (31.71%) | 50 (36.23%) | 0.8817 (0.5501–1.413) | 0.601 | 0.12 | .732 | |
| G | 499 (67.07%) | 579 (62.26%) | 1 | — | 168 (68.29%) | 88 (63.77%) | 1 | — | — | — | ||
| Additive | A/A | 31 (8.33%) | 67 (14.41%) | 0.7978 (0.6415–0.9922) | .0423 | 14 (11.38%) | 9 (13.04%) | 0.8865 (0.5585–1.407) | 0.6092 | 0.16 | — | |
| G/A | 183 (49.19%) | 217 (46.67%) | — | — | 50 (40.65%) | 32 (46.38%) | — | — | — | .686 | ||
| G/G | 158 (42.48%) | 181 (38.92%) | — | — | 59 (47.97%) | 28 v40.58%) | — | — | — | — | ||
a
Logistic regression: Corrected for sex, age, and BMI, p < .05 denotes significance.