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. 2022 Feb 7;12:786233. doi: 10.3389/fmicb.2021.786233

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Copyright © 2022 Colson, Fournier, Chaudet, Delerce, Giraud-Gatineau, Houhamdi, Andrieu, Brechard, Bedotto, Prudent, Gazin, Beye, Burel, Dudouet, Tissot-Dupont, Gautret, Lagier, Million, Brouqui, Parola, Fenollar, Drancourt, La Scola, Levasseur and Raoult.

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Chronological distribution of SARS-CoV-2 diagnoses by qPCR at IHU Méditerranée Infection institute (A), and of mean (± standard deviation) numbers of mutations in SARS-CoV-2 genomes obtained from patients sampled per month (B). (A) Chronological distribution of SARS-CoV-2 diagnoses is the mean number of diagnoses by qPCR per sliding windows of 7 days and steps of 1 day. (B) Numbers of mutations in SARS-CoV-2 genomes were calculated in reference to the genome of the Wuhan-Hu-1 isolate (GenBank Accession no. NC_045512.2). Whiskers indicate 10–90 percentiles. *p < 10^–1; ***p < 10^–3.