TABLE 1.

Top 30 cluster specified frequent biomarkers.

Marker name a	Frequency	Specified clusters	FDR
Atp5j2	$\frac{5}{10}$	Group1: Cluster0 vs. Group2: Rest all clusters	1.82 × 10–06
		Group1: Cluster1 vs. Group2: Rest all clusters	7.12 × 10–03
		Group1: Cluster3 vs. Group2: Rest all clusters	2.49, ×, 10–07
		Group1: Cluster6 vs. Group2: Rest all clusters	1.00, ×, 10–00
		Group1: Cluster7 vs. Group2: Rest all clusters	1.00, ×, 10–00
ERCC_00009	$\frac{5}{10}$	Group1: Cluster2 vs. Group2: Rest all clusters	8.69, ×, 10–28
		Group1: Cluster3 vs. Group2: Rest all clusters	2.08 × 10–02
		Group1: Cluster6 vs. Group2: Rest all clusters	4.82 × 10–05
		Group1: Cluster7 vs. Group2: Rest all clusters	3.24 × 10–01
		Group1: Cluster8 vs. Group2: Rest all clusters	1.14 × 10–04
Nedd4	$\frac{5}{10}$	Group1: Cluster0 vs. Group2: Rest all clusters	1.07 × 10–8
		Group1: Cluster3 vs. Group2: Rest all clusters	3.45 × 10–07
		Group1: Cluster4 vs. Group2: Rest all clusters	2.29, ×, 10–04
		Group1: Cluster5 vs. Group2: Rest all clusters	6.97 × 10–01
		Group1: Cluster9 vs. Group2: Rest all clusters	4.97 × 10–03
Abhd17a	$\frac{4}{10}$	Group1: Cluster1 vs. Group2: Rest all clusters	6.52 × 10–02
		Group1: Cluster2 vs. Group2: Rest all clusters	4.45 × 10–05
		Group1: Cluster6 vs. Group2: Rest all clusters	1.00, ×, 10–00
		Group1: Cluster7 vs. Group2: Rest all clusters	8.31 × 10–02
Actn1	$\frac{4}{10}$	Group1: Cluster0 vs. Group2: Rest all clusters	1.29, ×, 10–02
		Group1: Cluster4 vs. Group2: Rest all clusters	1.50, ×, 10–06
		Group1: Cluster5 vs. Group2: Rest all clusters	8.56 × 10–05
		Group1: Cluster9 vs. Group2: Rest all clusters	8.12 × 10–05
Arpc1b	$\frac{4}{10}$	Group1: Cluster0 vs. Group2: Rest all clusters	1.04 × 10–05
		Group1: Cluster1 vs. Group2: Rest all clusters	3.00, ×, 10–04
		Group1: Cluster3 vs. Group2: Rest all clusters	1.69, ×, 10–05
		Group1: Cluster8 vs. Group2: Rest all clusters	4.63 × 10–03
Atp5b	$\frac{4}{10}$	Group1: Cluster0 Vs Group2: Rest all clusters	7.59, ×, 10–11
		Group1: Cluster3 vs. Group2: Rest all clusters	2.34 × 10–05
		Group1: Cluster6 vs. Group2: Rest all clusters	9.96 × 10–05
		Group1: Cluster7 vs. Group2: Rest all clusters	1.00, ×, 10–04
B2m	$\frac{4}{10}$	Group1: Cluster0 vs. Group2: Rest all clusters	6.49, ×, 10–15
		Group1: Cluster1 vs. Group2: Rest all clusters	1.14 × 10–15
		Group1: Cluster3 vs. Group2: Rest all clusters	8.88 × 10–11
		Group1: Cluster9 Vs Group2: Rest all clusters	5.56 × 10–03
B4galnt2	$\frac{4}{10}$	Group1: Cluster0 vs. Group2: Rest all clusters	9.46 × 10–16
		Group1: Cluster1 vs. Group2: Rest all clusters	9.37 × 10–04
		Group1: Cluster3 vs. Group2: Rest all clusters	1.41 × 10–02
		Group1: Cluster4 vs. Group2: Rest all clusters	5.64 × 10–07
Calm1	$\frac{4}{10}$	Group1: Cluster1 vs. Group2: Rest all clusters	6.53 × 10–18
		Group1: Cluster3 vs. Group2: Rest all clusters	8.54 × 10–04
		Group1: Cluster5 vs. Group2: Rest all clusters	1.28 × 10–05
		Group1: Cluster9 vs. Group2: Rest all clusters	1.65 × 10–01
Cox5b	$\frac{4}{10}$	Group1: Cluster0 vs. Group2: Rest all clusters	1.72 × 10–14
		Group1: Cluster3 vs. Group2: Rest all clusters	9.78 × 10–07
		Group1: Cluster6 vs. Group2: Rest all clusters	5.75 × 10–01
		Group1: Cluster7 vs. Group2: Rest all clusters	1.18 × 10–03
Dhcr24	$\frac{4}{10}$	Group1: Cluster1 vs. Group2: Rest all clusters	3.35 × 10–10
		Group1: Cluster6 vs. Group2: Rest all clusters	3.83 × 10–03
		Group1: Cluster7 vs. Group2: Rest all clusters	1.15 × 10–04
		Group1: Cluster8 vs. Group2: Rest all clusters	4.44 × 10–01
Dpysl2	$\frac{4}{10}$	Group1: Cluster4 vs. Group2: Rest all clusters	3.26 × 10–05
		Group1: Cluster5 vs. Group2: Rest all clusters	2.29, ×, 10–05
		Group1: Cluster8 vs. Group2: Rest all clusters	8.48 × 10–08
		Group1: Cluster9 vs. Group2: Rest all clusters	6.19, ×, 10–01
Dst	$\frac{4}{10}$	Group1: Cluster1 vs. Group2: Rest all clusters	1.34 × 10–06
		Group1: Cluster5 vs. Group2: Rest all clusters	8.44 × 10–03
		Group1: Cluster8 vs. Group2: Rest all clusters	4.38 × 10–03
		Group1: Cluster9 vs. Group2: Rest all clusters	3.29, ×, 10–02
Eef1a1	$\frac{4}{10}$	Group1: Cluster0 vs. Group2: Rest all clusters	2.84 × 10–36
		Group1: Cluster4 vs. Group2: Rest all clusters	1.85 × 10–03
		Group1: Cluster5 vs. Group2: Rest all clusters	4.43 × 10–02
		Group1: Cluster9 vs. Group2: Rest all clusters	6.96 × 10–01
ERCC_00003	$\frac{4}{10}$	Group1: Cluster1 vs. Group2: Rest all clusters	8.53 × 10–07
		Group1: Cluster2 vs. Group2: Rest all clusters	6.58 × 10–10
		Group1: Cluster3 vs. Group2: Rest all clusters	3.11 × 10–07
		Group1: Cluster8 vs. Group2: Rest all clusters	4.55 × 10–19
ERCC_00043	$\frac{4}{10}$	Group1: Cluster1 vs. Group2: Rest all clusters	3.14 × 10–09
		Group1: Cluster2 vs. Group2: Rest all clusters	4.50, ×, 10–10
		Group1: Cluster3 vs. Group2: Rest all clusters	5.90, ×, 10–03
		Group1: Cluster8 vs. Group2: Rest all clusters	2.37 × 10–27
ERCC_0007	$\frac{4}{10}$	Group1: Cluster1 vs. Group2: Rest all clusters	1.04 × 10–06
		Group1: Cluster2 vs. Group2: Rest all clusters	7.88 × 10–02
		Group1: Cluster3 vs. Group2: Rest all clusters	9.58 × 10–12
		Group1: Cluster8 vs. Group2: Rest all clusters	6.17 × 10–18
Fdps	$\frac{4}{10}$	Group1: Cluster1 vs. Group2: Rest all clusters	4.45 × 10–04
		Group1: Cluster2 vs. Group2: Rest all clusters	6.28 × 10–01
		Group1: Cluster6 vs. Group2: Rest all clusters	1.91 × 10–08
		Group1: Cluster7 vs. Group2: Rest all clusters	8.40, ×, 10–05
Glud1	$\frac{4}{10}$	Group1: Cluster0 vs. Group2: Rest all clusters	9.60, ×, 10–05
		Group1: Cluster3 vs. Group2: Rest all clusters	3.21 × 10–01
		Group1: Cluster5 vs. Group2: Rest all clusters	2.70, ×, 10–11
		Group1: Cluster9 vs. Group2: Rest all clusters	2.21 × 10–07
Hsp90b1	$\frac{4}{10}$	Group1: Cluster0 vs. Group2: Rest all clusters	2.48 × 10–03
		Group1: Cluster4 vs. Group2: Rest all clusters	8.20, ×, 10–04
		Group1: Cluster5 vs. Group2: Rest all clusters	7.20, ×, 10–01
		Group1: Cluster9 vs. Group2: Rest all clusters	3.15 × 10–06
Malat1	$\frac{4}{10}$	Group1: Cluster1 vs. Group2: Rest all clusters	2.38 × 10–12
		Group1: Cluster2 vs. Group2: Rest all clusters	1.91 × 10–02
		Group1: Cluster5 vs. Group2: Rest all clusters	2.98 × 10–06
		Group1: Cluster9 vs. Group2: Rest all clusters	2.76 × 10–07
Rpl17	$\frac{4}{10}$	Group1: Cluster0 vs. Group2: Rest all clusters	1.34 × 10–39
		Group1: Cluster3 vs. Group2: Rest all clusters	1.00, ×, 10–00
		Group1: Cluster4 vs. Group2: Rest all clusters	1.16 × 10–02
		Group1: Cluster9 vs. Group2: Rest all clusters	8.70, ×, 10–01
Rpl4	$\frac{4}{10}$	Group1: Cluster0 vs. Group2: Rest all clusters	3.65 × 10–35
		Group1: Cluster3 vs. Group2: Rest all clusters	7.05 × 10–02
		Group1: Cluster4 vs. Group2: Rest all clusters	9.36 × 10–03
		Group1: Cluster9 vs. Group2: Rest all clusters	1.00, ×, 10–00
Rpl7	$\frac{4}{10}$	Group1: Cluster0 vs. Group2: Rest all clusters	5.36 × 10–29
		Group1: Cluster4 vs. Group2: Rest all clusters	3.64 × 10–01
		Group1: Cluster6 vs. Group2: Rest all clusters	3.68 × 10–01
		Group1: Cluster9 vs. Group2: Rest all clusters	1.00, ×, 10–00
Rps6	$\frac{4}{10}$	Group1: Cluster0 vs. Group2: Rest all clusters	1.39, ×, 10–29
		Group1: Cluster4 vs. Group2: Rest all clusters	5.02 × 10–03
		Group1: Cluster6 vs. Group2: Rest all clusters	1.00, ×, 10–00
		Group1: Cluster9 vs. Group2: Rest all clusters	3.52 × 10–01
Sox9	$\frac{4}{10}$	Group1: Cluster0 Vs Group2: Rest all clusters	3.56 × 10–06
		Group1: Cluster4 vs. Group2: Rest all clusters	1.63 × 10–10
		Group1: Cluster5 vs. Group2: Rest all clusters	1.81 × 10–01
		Group1: Cluster9 vs. Group2: Rest all clusters	1.19, ×, 10–03
Tkt	$\frac{4}{10}$	Group1: Cluster1 vs. Group2: Rest all clusters	1.24 × 10–05
		Group1: Cluster2 vs. Group2: Rest all clusters	5.81 × 10–05
		Group1: Cluster6 vs. Group2: Rest all clusters	1.68 × 10–02
		Group1: Cluster7 vs. Group2: Rest all clusters	2.44 × 10–01
Tm9sf3	$\frac{4}{10}$	Group1: Cluster0 vs. Group2: Rest all clusters	1.42 × 10–03
		Group1: Cluster4 vs. Group2: Rest all clusters	2.90, ×, 10–14
		Group1: Cluster5 vs. Group2: Rest all clusters	1.98 × 10–02
		Group1: Cluster9 vs. Group2: Rest all clusters	1.77 × 10–03
Ywhae	$\frac{4}{10}$	Group1: Cluster0 vs. Group2: Rest all clusters	3.64 × 10–09
		Group1: Cluster3 vs. Group2: Rest all clusters	3.75 × 10–08
		Group1: Cluster5 vs. Group2: Rest all clusters	9.12 × 10–05
		Group1: Cluster9 vs. Group2: Rest all clusters	2.26 × 10–02

^aSee Supplementary Table S2 for details.