TABLE 3.
Top significant KEGG Pathways (FDR sorted).
| KEGG pathway name a | #genes | Enriched Adjusted p-value | FDR |
|---|---|---|---|
| mmu03010:Ribosome | 112 | 7.54 × 10–40 | 5.17 × 10–40 |
| mmu01100:Metabolic pathways | 477 | 3.97 × 10–33 | 1.36 × 10–33 |
| mmu01130:Biosynthesis of antibiotics | 124 | 5.34 × 10–25 | 1.22 × 10–25 |
| mmu00190:Oxidative phosphorylation | 89 | 3.77 × 10–22 | 2.58 × 10–22 |
| mmu05016:Huntington’s disease | 111 | 1.50, ×, 10–20 | 2.05 × 10–21 |
| mmu05012:Parkinson’s disease | 90 | 2.79, ×, 10–19 | 3.19, ×, 10–20 |
| mmu05010:Alzheimer’s disease | 100 | 1.19, ×, 10–18 | 1.16 × 10–19 |
| mmu04932:Non-alcoholic fatty liver disease (NAFLD) | 86 | 1.14 × 10–14 | 9.74 × 10–16 |
| mmu01200:Carbon metabolism | 70 | 1.50, ×, 10–14 | 1.14 × 10–15 |
| mmu03040:Spliceosome | 74 | 9.63 × 10–13 | 6.57 × 10–14 |
a
See Supplementary Table S3 for details.