Table 5. GSEA pathways up-regulated due to high expression of IGF2BP2.
| Gene set name | NES | NOM P-val | FDR q-val |
|---|---|---|---|
| KEGG_CELL_CYCLE | 2.144 | 0.000 | 0.011 |
| KEGG_RNA_DEGRADATION | 2.101 | 0.000 | 0.011 |
| KEGG_UBIQUITIN_MEDIATED_PROTEOLYSIS | 2.007 | 0.000 | 0.011 |
| KEGG_OOCYTE_MEIOSIS | 2.070 | 0.002 | 0.006 |
| KEGG_SPLICEOSOME | 2.096 | 0.002 | 0.007 |
| KEGG_NUCLEOTIDE_EXCISION_REPAIR | 2.058 | 0.002 | 0.007 |
| KEGG_BASAL_TRANSCRIPTION_FACTORS | 2.032 | 0.002 | 0.009 |
| KEGG_PYRIMIDINE_METABOLISM | 1.952 | 0.004 | 0.020 |
| KEGG_WNT_SIGNALING_PATHWAY | 1.838 | 0.004 | 0.034 |
| KEGG_HOMOLOGOUS_RECOMBINATION | 1.931 | 0.004 | 0.022 |
| KEGG_PROGESTERONE_MEDIATED_OOCYTE_MATURATION | 1.866 | 0.004 | 0.034 |
| KEGG_ENDOCYTOSIS | 1.846 | 0.004 | 0.034 |
| KEGG_SMALL_CELL_LUNG_CANCER | 1.851 | 0.004 | 0.034 |
| KEGG_RNA_POLYMERASE | 1.831 | 0.006 | 0.034 |
| KEGG_BASE_EXCISION_REPAIR | 1.900 | 0.006 | 0.028 |
| KEGG_PANCREATIC_CANCER | 1.806 | 0.006 | 0.039 |
| KEGG_AMINOACYL_TRNA_BIOSYNTHESIS | 1.799 | 0.008 | 0.039 |
| KEGG_INOSITOL_PHOSPHATE_METABOLISM | 1.866 | 0.008 | 0.037 |
| KEGG_N_GLYCAN_BIOSYNTHESIS | 1.864 | 0.008 | 0.032 |
| KEGG_BLADDER_CANCER | 1.615 | 0.008 | 0.079 |
| KEGG_THYROID_CANCER | 1.766 | 0.008 | 0.042 |
| KEGG_CHRONIC_MYELOID_LEUKEMIA | 1.772 | 0.008 | 0.045 |
| KEGG_PENTOSE_PHOSPHATE_PATHWAY | 1.660 | 0.008 | 0.067 |
| KEGG_PURINE_METABOLISM | 1.754 | 0.010 | 0.043 |
| KEGG_NOTCH_SIGNALING_PATHWAY | 1.769 | 0.010 | 0.042 |
| KEGG_RENAL_CELL_CARCINOMA | 1.788 | 0.010 | 0.040 |
| KEGG_PATHWAYS_IN_CANCER | 1.700 | 0.012 | 0.056 |
| KEGG_REGULATION_OF_ACTIN_CYTOSKELETON | 1.718 | 0.014 | 0.051 |
| KEGG_CYSTEINE_AND_METHIONINE_METABOLISM | 1.745 | 0.014 | 0.042 |
| KEGG_ADHERENS_JUNCTION | 1.811 | 0.016 | 0.039 |
| KEGG_DNA_REPLICATION | 1.797 | 0.016 | 0.038 |
| KEGG_MISMATCH_REPAIR | 1.753 | 0.016 | 0.042 |
| KEGG_FRUCTOSE_AND_MANNOSE_METABOLISM | 1.619 | 0.018 | 0.081 |
| KEGG_CYTOSOLIC_DNA_SENSING_PATHWAY | 1.754 | 0.018 | 0.045 |
| KEGG_ERBB_SIGNALING_PATHWAY | 1.707 | 0.018 | 0.054 |
| KEGG_P53_SIGNALING_PATHWAY | 1.722 | 0.018 | 0.051 |
| KEGG_PROTEASOME | 1.771 | 0.019 | 0.043 |
| KEGG_GLYCOSYLPHOSPHATIDYLINOSITOL_GPI_ANCHOR_BIOSYNTHESIS | 1.695 | 0.020 | 0.056 |
| KEGG_AMINO_SUGAR_AND_NUCLEOTIDE_SUGAR_METABOLISM | 1.623 | 0.021 | 0.081 |
| KEGG_PROTEIN_EXPORT | 1.681 | 0.023 | 0.061 |
| KEGG_PATHOGENIC_ESCHERICHIA_COLI_INFECTION | 1.641 | 0.023 | 0.075 |
| KEGG_GLIOMA | 1.585 | 0.025 | 0.093 |
| KEGG_PHOSPHATIDYLINOSITOL_SIGNALING_SYSTEM | 1.604 | 0.026 | 0.084 |
| KEGG_GLYOXYLATE_AND_DICARBOXYLATE_METABOLISM | 1.619 | 0.030 | 0.079 |
| KEGG_NEUROTROPHIN_SIGNALING_PATHWAY | 1.572 | 0.031 | 0.099 |
| KEGG_ADIPOCYTOKINE_SIGNALING_PATHWAY | 1.534 | 0.032 | 0.108 |
| KEGG_ONE_CARBON_POOL_BY_FOLATE | 1.677 | 0.033 | 0.061 |
| KEGG_LONG_TERM_POTENTIATION | 1.496 | 0.042 | 0.126 |
| KEGG_INSULIN_SIGNALING_PATHWAY | 1.540 | 0.045 | 0.108 |
| KEGG_VASOPRESSIN_REGULATED_WATER_REABSORPTION | 1.514 | 0.045 | 0.118 |
| KEGG_GLYCEROPHOSPHOLIPID_METABOLISM | 1.469 | 0.046 | 0.139 |
| KEGG_EPITHELIAL_CELL_SIGNALING_IN_HELICOBACTER_PYLORI_INFECTION | 1.535 | 0.046 | 0.109 |
| KEGG_ENDOMETRIAL_CANCER | 1.553 | 0.049 | 0.105 |
| KEGG_ALANINE_ASPARTATE_AND_GLUTAMATE_METABOLISM | 1.542 | 0.049 | 0.110 |
Abbreviation: NES, normalized enrichment score. Gene sets with NES > 1, NOM P-value <0.05 and FDR q-value <0.1 are considered as significant.