Table 1.
Type of test | Intended use | Caution |
---|---|---|
rRT-PCR | Confirmatory diagnosis in acute symptomatic patients or screening of asymptomatic individuals | Not suitable for quantitative interpretation. Infectivity cannot be determined on the basis of PCR results alone. |
Pooled test using rRT-PCR | Screening of asymptomatic individuals | Sensitivity may vary with the transport medium, nucleic acid extraction method, and PCR reagent used, and the pool size. |
Rapid molecular test | Rapid screening under emergency situations | Positive results are recommended to be confirmed with a validated rRT-PCR. |
Antigen test | Diagnosis for symptomatic patients within seven days from symptom onset | The false-negative rate is high in pre-symptomatic or asymptomatic patients. The false-positive rate is high when prevalence is low. |
Antibody test | Confirmation of past infection or multisystem inflammation syndrome or serosurveillance | Assays with high specificity should be used. Not recommended for evaluating the risk of infection. |
Abbreviation: rRT-PCR, real-time reverse transcription PCR.