Table 1.
Mouse weights and serum cholesterol levels
| Sex | Weeks on western diet | Weight (gm) |
Serum (cholesterol), mmol/L (mg/dL) |
||
|---|---|---|---|---|---|
| Dbn flox/flox/Ldlr−/− (n = 20) | SMC-Dbn−/−/Ldlr−/− (n = 19) |
Dbn
flox/flox/Ldlr−/− (n = 14) |
SMC-Dbn−/−/Ldlr−/− (n = 14) |
||
| Male | 14 | 37 ± 1 | 37 ± 1 | 22 ± 1 (830 ± 50) | 21 ± 1 (820 ± 60) |
| 20 | 40 ± 2 | 40 ± 1 | 28 ± 1 (1090 ± 40) | 29 ± 1 (1130 ± 40) | |
| Female | 14 | 25 ± 1 | 26 ± 1 | 31 ± 1 (1190 ± 60) | 31 ± 1 (1200 ± 100) |
Mice of the indicated genotype and sex were fed a western diet for the indicated number of weeks, euthanized, and then subjected to the indicated measurements.