Table 1.
MIS-C | KD | |
Age | 0-19 years 8 (median age 8-99) | <5 years 3 (median age 39) |
Geographic Area | Europe, North America, South America 9 | Asia (Japan, South Korea, Taiwan) 3 |
Clinical similarities8,10 | Fever ⩾ 3 days | Fever ⩾ 5 days |
Rash | Polymorphous rash | |
Bilateral non-purulent conjunctivitis | Bilateral non-purulent conjunctivitis | |
Mucocutaneous inflammation signs (oral, hands, feet) | Oral mucous membrane changes (cracked and erythematous lips, strawberry tongue) | |
Cardiovascular: Features of myocardial dysfunction, pericarditis, valvulitis, or coronary abnormalities | Changes in extremities (erythema of hands and feet, desquamation) | |
Gastrointestinal: Diarrhea, vomiting, abdominal pain | Cardiovascular: Coronary artery abnormalities, decreased LV function, mitral regurgitation, pericardial effusion | |
Gastrointestinal: Diarrhea, nausea, vomiting, abdominal pain |
Abbreviations: KD, Kawasaki disease; LV, left ventricle; MIS-C, multisystem inflammatory syndrome related to COVID-19.