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. 2022 Feb 17;12(1 Suppl):109S–121S. doi: 10.1177/21925682211052920

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© The Author(s) 2022

This article is distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs 4.0 License (https://creativecommons.org/licenses/by-nc-nd/4.0/) which permits non-commercial use, reproduction and distribution of the work as published without adaptation or alteration, without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).

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Figure 3. — Technological readiness of a number of contemporary therapies in the 3 broad categories of neuroprotection, neuromodulation and neuroregeneration. Stage 1 indicates therapies that are predominantly in preclinical developmental stage and will require further research at this stage. Stage 2 shows technologies that are developed, though require further early stage testing and exploration of protocols in degenerative cervical myelopathy prior to phase-III efficacy trials. These may have been investigated in chronic cervical SCI population. Stage 3 shows therapies which are mature in development and may be considered for investigation in degenerative cervical myelopathy at an earlier timeframe. Graphics developed with the support of Myelopathy.org. *These therapies have undergone or are currently undergoing phase-III trials.