Table 2.
Events | Event rate per 100 PY | 1-year CIP (95% CI) | Unadjusted HR (95% CI) | Adjusted HR (95% CI) | Weighted HR† (95% CI) | ||
---|---|---|---|---|---|---|---|
Any CIED infection | Non-TP | 227 | 0.66 (0.58–0.75) | 0.61 (0.53–0.69) | Ref. | Ref. | Ref. |
TP | 19 | 0.75 (0.48–1.18) | 0.65 (0.36–0.95) | 1.28 (0.80–2.05) | 0.85 (0.51–1.42) | 0.56 (0.29–1.13) | |
Systemic CIED infection | Non-TP | 123 | 0.36 (0.30–0.43) | 0.33 (0.27–0.39) | Ref. | Ref. | Ref. |
TP | 15 | 0.60 (0.36–0.99) | 0.52 (0.26–0.79) | 1.84 (1.07–3.16) | 0.99 (0.54–1.80) | 0.74 (0.33–1.69) | |
Hospitalization for IE‡ | Non-TP | 124 | 0.36 (0.31–0.43) | 0.33 (0.28–0.40) | Ref. | Ref. | Ref. |
TP | 27 | 1.12 (0.7-1.63) | 0.97 (0.61-1.34) | 3.07 (2.01-4.68) | 1.68 (1.06-2.67) | 1.49 (0.89-2.51) | |
All-cause mortality | Non-TP | 3158 | 8.82 (8.52–9.13) | 8.39 (8.11–8.67) | Ref. | Ref. | Ref. |
TP | 497 | 18.87 (17.28–20.61) | 16.84 (15.53–18.23) | 1.92 (1.75–2.11) | 1.36 (1.13–1.64) | 1.57 (1.34–1.84) |
CIED = cardiac implantable electronic device; CIP = cumulative incidence proportion; IE = infective endocarditis; PS = propensity score; PY = person-years; TP = temporary transvenous pacing.
Estimated using stabilized inverse probability of treatment weights based on propensity scores.
Excluding patients with prior hospitalization(s) for endocarditis (n = 362).