Table 1.
Subject Characteristics
| Variable | All (N=63) | Females (N=48) | Males (N=15) | Pvalue |
|---|---|---|---|---|
| Age (years), median (IQR) | 39 (28–45) | 38 (27–45) | 39 (29–44) | 0.57 |
| BMI (kg/m2), median (IQR) | 32.9 (30.2–34.4) | 32.9 (30.6–34.4) | 33.1 (26.1–34.9) | 0.91 |
| Fat (%), median (IQR) | 44 (39–47) | 45 (41–48) | 37 (26–39) | <0.001 |
| FFM (kg), median (IQR) | 51.1 (45.8–58.7) | 48.3 (44.8–52.7) | 66.7 (62.2–71.6) | <0.001 |
| UBSQ fat (kg), median (IQR) | 21.0 (16.7–24.5) | 22.1 (17.6–24.7) | 20.7 (10.6–22.2) | 0.18 |
| Visceral Fat (kg), median (IQR) | 3.4 (2.2–5.6) | 3.1(2.1–4.5) | 6.6 (2.7–7.7) | <0.001 |
| Leg fat (kg), median (IQR) | 13.4 (10.9–15.9) | 14.2 (12.3–17.3) | 10.5 (7.2–11.5) | <0.001 |
| Abdominal fat cell size (μg/cell), median (IQR) | 0.72 (0.48–0.99) | 0.72 (0.50–0.94) | 0.71 (0.39–1.11) | 0.85 |
| Femoral fat cell size (μg/cell), median (IQR) | 0.96 (0.71–1.16) | 0.97 (0.74–1.21) | 0.76 (0.59–0.97) | 0.05 |
| Fasting plasma glucose (mg/dL), median (IQR) | 90 (84–94) | 87 (84–92) | 90 (86–99) | 0.09 |
| Abdominal SaβGal (%) a (N=59), median (IQR) | 1.8 (0.9–3.7) | 2.0 (0.9–4.0) | 1.5 (0.6–2.3) | 0.09 |
| Femoral SaβGal (%) a (N=58), median (IQR) | 3.4 (2.3–5.1) | 3.9 (2.7–5.3) | 2.1 (0.7–3.3) | 0.002 |
P-values refers to the difference between males and females.
a
Senescence associated β-galactosidase staining was used to measure senescent cells. BMI - body mass index; FFM - fat free mass; UBSQ - upper body subcutaneous; SaβGal - senescence associated β-galactosidase.