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. 2022 Jan 28;13:786501. doi: 10.3389/fgene.2022.786501

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Copyright © 2022 Aljogol, Thompson, Osborne and Mifsud.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Reproducibility of HiCUP-preprocessed significant interactions. (A). Number of HiCUP-preprocessed significant interactions using GOTHiC (with and without LF), CHiCAGO, CHiCANE and CHiCMaxima. (B). Bar plots represent the percentage of non-baited fragments that overlap in at least two replicates for each bait. Overlaps were studied for exact fragment-level interactions and interactions where non-baited fragment-ends were extended by 2.5 kb or 20 kb.