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. Author manuscript; available in PMC: 2022 Feb 21.
Published in final edited form as: Med Phys. 2021 Jul 9;48(8):4375–4386. doi: 10.1002/mp.15038

Table 3:

Linear mixed-effects model results using GE and Helical High Dose protocol as the reference for vendor and protocol, respectively. In this model, CT measurement depends on the true fat-fraction of each vial with fixed effects from vendor and protocol. CT number has high correlation with MRI-PDFF in a relationship with slope of −1.84±0.01 HU/%, intercept of 67.8±2.9 HU, and R2=0.997. CT vendor selection has a significant contribution (p<0.005) to the CT number versus MRI-PDFF calibration relationship (i.e., slope and intercept), however, CT protocol selection has no significant contribution (p>0.1) to the CT number versus MRI-PDFF calibration relationship (i.e., slope and intercept). PDFF, proton density fat-fraction.

Coef. Std.Err. p 95% CI
Slope (HU/%) Reference (GE) −1.841 0.007 <0.001 [−1.855, −1.827]
Vendor Siemens 0.055 0.006 <0.001 [0.043, 0.067]
Philips 0.024 0.008 <0.005 [0.008, 0.040]
Protocol Axial High Dose −0.003 0.009 0.774 [−0.020, 0.015]
Axial Low Dose −0.001 0.009 0.968 [−0.018, 0.017]
Helical Low Dose 0.004 0.009 0.685 [−0.014, 0.021]
AAPM 0.013 0.009 0.154 [−0.005, 0.031]
Intercept (HU) Reference (Helical High Dose) 67.8 2.9 <0.001 [62.1, 73.4]
Vendor Siemens −5.6 0.2 <0.001 [−6.0, −5.1]
Philips −3.0 0.3 <0.001 [−3.6, −2.4]
Protocol Axial High Dose −0.1 0.3 0.798 [−0.7, 0.6]
Axial Low Dose −0.4 0.3 0.188 [−1.1, 0.2]
Helical Low Dose −0.4 0.3 0.231 [−1.1, 0.3]
AAPM −0.4 0.3 0.288 [−1.0, 0.3]

Note: Coef., coefficient; Std.Err., standard error; 95% CI, 95% confidence interval; AAPM, American Association of Physicists in Medicine.