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. 2011 Apr 13;2011(4):CD004919. doi: 10.1002/14651858.CD004919.pub2

Summary of findings for the main comparison. Immediate success rate of reduction.

intra‐articular lignocaine compared to intravenous analgesia with or without sedation for acute anterior shoulder dislocation in adults
Patient or population: acute anterior shoulder dislocation in adults 
 Settings: Emergency Department 
 Intervention: intra‐articular lignocaine 
 Comparison: intravenous analgesia with or without sedation
Outcomes Illustrative comparative risks* (95% CI) Relative effect 
 (95% CI) No of Participants 
 (studies) Quality of the evidence 
 (GRADE) Comments
Assumed risk Corresponding risk
intravenous analgesia with or without sedation intra‐articular lignocaine
Per cent of patients who underwent successful reduction Study population RR 0.95 
 (0.83 to 1.1) 211 
 (5 studies) ⊕⊕⊝⊝ 
 low1,2  
776 per 1000 737 per 1000 
 (644 to 854)
Medium risk population
792 per 1000 752 per 1000 
 (657 to 871)
*The basis for the assumed risk (e.g. the median control group risk across studies) is provided in footnotes. The corresponding risk (and its 95% confidence interval) is based on the assumed risk in the comparison group and the relative effect of the intervention (and its 95% CI). 
 CI: Confidence interval; RR: Risk ratio;
GRADE Working Group grades of evidence 
 High quality: Further research is very unlikely to change our confidence in the estimate of effect. 
 Moderate quality: Further research is likely to have an important impact on our confidence in the estimate of effect and may change the estimate. 
 Low quality: Further research is very likely to have an important impact on our confidence in the estimate of effect and is likely to change the estimate. 
 Very low quality: We are very uncertain about the estimate.

1 Relatively small number of included studies. 
 2 Small sample size in each included study.