TABLE 2.
Cohort 1 | Cohort 2 | ||||||||
---|---|---|---|---|---|---|---|---|---|
Time point | t 0 | t 1 | t 2 | t 3 | t 0 | t 1 | t 2 | t 3 | t 4 |
Month | 0 | 6 | 12 | 18 | 0 | 6 | 12 | 18 | 24 |
Exercise testing | |||||||||
Incremental exercise test a | |||||||||
- Twelve-lead-electrocardiogram | X | X | X | X | X | ||||
- Blood pressure | X | X | X | X | X | ||||
- Capillary blood lactate b | X | X | X | X | X | ||||
- Rate of perceived exertion (BORG-scale) c | X | X | X | X | X | ||||
- Pulse oximetry | X | X | X | X | X | ||||
- Breath gas analysis/Spiroergometry (optional) d | X | X | X | X | X | ||||
Additional ramp test (if possible) e | |||||||||
- Breath gas analysis/Spiroergometry f | X | X | |||||||
- Capillary blood lactate (pre/post exercise) | X | X | |||||||
- Capillary blood gases | X | X |
Treadmill, bicycle, canoe or rowing ergometry with stepwise increase of exercise load until voluntary exhaustion. The incremental exercise test is performed in both cohorts.
Calculation of exercise load at the lactate threshold (LT), individual anaerobic threshold (IAT) and at the end of exercise from the lactate-performance curve.
Assessment of perceived exertion (RPE) pre-exercise, at the end of every stage during the test and post-exercise according the qualities “overall,” “muscular,” and “ventilatory.”
Additional breath gas analysis is performed in cases where breath gas analysis was also performed in an existing previous test.
An additional ramp test with breath gas analysis is performed only in C1 provided that the athletes tolerate a second test. Protocol: bicycle ergometry, starting at an initial load of .5 W per kilogram body mass with a continuous increment of .5 W per kilogram body mass until voluntary exhaustion.
Measures: maximum oxygen consumption (VO2max), ventilatory threshold 1 (VT1), respiratory compensation point (RCP), maximum minute ventilation (VEmax), tidal volume, oxygen pulse, ventilatory equivalents (VE/VO2 and VE/VCO2), endtidal VCO2 (ET- VCO2).