Table 4.
Components of the PLASMIC score by age for patients with TTP
| Age Group (years) | ||||
|---|---|---|---|---|
| 18–39 (n = 35) |
40–59 (n = 23) |
≥ 60 (n = 13) |
p-value | |
| PLASMIC score | 5.97 ± 0.18 | 5.26 ± 1.79 | 5.15 ± 1.34 | 0.031 |
| Platelet (×109/uL) | 19.87 ± 2.75 | 28.60 ± 5.96 | 35.14 ± 8.59 | 0.031 |
| Serum creatinine (mg/dL) | 1.63 ± 0.20 | 2.14 ± 0.78 | 2.03 ± 0.42 | 0.330 |
| PLASMIC score point category | ||||
| Hemolysis | 85.7% | 88.5% | 84.6% | 0.622 |
| Cancer | 94.6% | 92.6% | 78.6% | 0.120 |
| Transplant | 97.3% | 100.0% | 100.0% | 0.725 |
| MCV | 60.0% | 41.7% | 46.2% | 0.296 |
| INR | 91.4% | 84.0% | 84.6% | 0.413 |
| Platelet | 81.6% | 70.4% | 50.0% | 0.030 |
| Creatinine | 83.8% | 84.6% | 69.2% | 0.229 |
Abbreviations: MCV, mean corpuscular volume; INR, international normalized ratio.
Note: Reported p-values compared age groups 18–39 vs ≥ 60 years old. P-values comparing age groups 18–39 vs 40–59 and 40–59 vs ≥ 60 years old were nonsignificant and not included in this table.