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Schematic showing the methodology used to control the composition of P22 nanoreactors. Nanoreactors were co-assembled in vitro with AdhD-SP and wtSP to control the loading of cargo macromolecules. A constant amount of CP was added to variable ratios of wtSP and AdhD-SP and allowed to self-assemble in vitro. Subsequently, the wtSP was selectively removed from these co-assembled nanoreactors to alter the packing density of enzymes inside P22.
