Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Thermodynamic Solubility of Selected Analoguesa
| compd | μM | (μg/mL) | initial dose concentration (mg/mL) | pH after assay |
|---|---|---|---|---|
| 1 (brequinar) | 1085.2 | 407.4 | 6.2 | 7.4 |
| 1048.6 | 393.6 | 6.4 | 7.4 | |
| 3 | 43.9 | 14.5 | 2.9 | 7.4 |
| 48.0 | 15.9 | 4.9 | 7.4 | |
| 41 | 1000.1 | 392.8 | 5.8 | 7.4 |
| 982.1 | 385.8 | 4.9 | 7.4 | |
| 46 | 2628.4 | 894.6 | 6.7 | 7.4 |
| 3096.3 | 1053.6 | 8.7 | 7.4 |
Assay performed using CLND in phosphate buffer saline, pH 7.4. Each entry lists a single run. Analyte concentrations were determined via a standard calibration curve.
