Table 4.

Comparison of urinary indices in intervention and control groups at different times using one-way ANOVA test.

Urinary indicators	Time	Melatonin group (N = 36)		Control group (N = 30)		Within group P-value	Between-group P-value
		Mean	SD	Mean	SD
BUN (mg/dL)	Baseline	569.04	333.7	595.5	257.4	< 0.04	0.03
	24 h later	482.04	327.04	680.7	246.7
	5 days later	573.9	476.2	763.3	306.9
Creatinine (mg/dL)	Baseline	117.3	81.9	125.1	87.4	< 0.13	0.92
	24 h later	110.9	53.9	110.3	59.4
	5 days later	121.18	75.7	122	61.7
Magnesium (mg/dL)	Baseline	3.5	1.1	3.6	1.2	< 0.02	0.04
	24 h later	3.1	1.1	3.2	1.2
	5 days later	3.3	1.04	3.8	1.1
Sodium (mEq/L)	Baseline	117.9	52.9	153.4	55.9	0.04	0.003
	24 h later	115.3	40.4	125.5	36.5
	5 days later	115	40.6	154.8	54.1
Potassium (mmol/L)	Baseline	57.9	36.3	48.1	30.7	0.049	0.04
	24 h later	41.3	28.8	54.5	29.8
	5 days later	41.6	28.8	57.9	42.2
Sodium extraction fraction (%)	Baseline	1.3	0.9	1.4	1.1	0.26	0.32
	24 h later	1.6	1.1	1.1	0.8
	5 days later	2.03	1.4	1.5	1.2
Magnesium extraction fraction (%)	Baseline	4.2	2.2	3.1	1.8	0.56	0.09
	24 h later	4.7	2.7	2.8	1.2
	5 days later	4.9	2.7	3.7	1.6

BUN, Blood urea nitrogen.