Hausberg 2001.

Methods	Study design: parallel RCT Time frame: NS Follow‐up period: 6 months
Participants	Setting: single centre Country: Germany SCr < 2.5 mg/dL, TC 200 to 350 mg/dL Number: treatment group (18); control group (18) Mean age ± SEM (years): treatment group (50 ± 2); control group (47 ± 3) Sex (M/F): treatment group (13/5); control group (13/5) Exclusion criteria: prior use of statins; previous history of cardiovascular disease
Interventions	Treatment group Fluvastatin 40 mg/d Control group Placebo
Outcomes	Lipid parameters (TC, LDL, HDL, TG) Flow mediated vasodilation CK levels
Notes
Risk of bias
Bias	Authors' judgement	Support for judgement
Random sequence generation (selection bias)	Unclear risk	Not described
Allocation concealment (selection bias)	Unclear risk	Not described
Blinding of participants and personnel (performance bias) All outcomes	Low risk	Double blinded
Blinding of outcome assessment (detection bias) All outcomes	Unclear risk	Not described
Incomplete outcome data (attrition bias) All outcomes	High risk	4/40 patients (10%) dropped out during follow‐up
Intention to treat analysis	High risk	Not performed