Table 3.
Procalcitonin at different cutoff points on primary and secondary outcomes
| Outcome | Cut-off value PCT | Odds ratio | Confidence interval | Sensitivity | Specificity | Negative predictive value | Positive predictive value |
|---|---|---|---|---|---|---|---|
| Severe outcome | Continuous scale | 4.19 | (2.52–7.69) | ||||
| 0.25 (ng/mL) | 9.76 | (5.79–16.83) | 0.67 | 0.82 | 0.84 | 0.63 | |
| 0.5 (ng/mL) | 12.12 | (6.61–23.2) | 0.49 | 0.92 | 0.79 | 0.75 | |
| 1 (ng/mL) | 14.40 | (6.45–36.77) | 0.31 | 0.96 | 0.75 | 0.82 | |
| Hospital admission | Continuous scale | 1667.00 | (67.91–98,005.22) | ||||
| 0.25 (ng/mL) | 14.68 | (5.27–61.11) | 0.40 | 0.95 | 0.28 | 0.97 | |
| 0.5 (ng/mL) | 22.78 | (4.88–406.11) | 0.25 | 0.98 | 0.25 | 0.98 | |
| 1 (ng/mL) | NA | NA | 0.15 | 1 | 0.22 | 1 | |
| ICU admission | Continuous scale | 1.15 | (1.05–1.3) | ||||
| 0.25 (ng/mL) | 5.94 | (3.36–10.79) | 0.66 | 0.74 | 0.90 | 0.39 | |
| 0.5 (ng/mL) | 7.70 | (4.24–14.2) | 0.53 | 0.87 | 0.88 | 0.50 | |
| 1 (ng/mL) | 8.93 | (4.42–18.51) | 0.36 | 0.93 | 0.85 | 0.6 | |
| Mortality | Continuous scale | 1.22 | (1.08–1.43) | ||||
| 0.25 (ng/mL) | 9.72 | (5.2–19.08) | 0.75 | 0.76 | 0.93 | 0.41 | |
| 0.5 (ng/mL) | 9.38 | (5.08–17.68) | 0.57 | 0.87 | 0.90 | 0.50 | |
| 1 (ng/mL) | 7.93 | (3.92–16.29) | 0.36 | 0.93 | 0.86 | 0.55 |
ICU intensive care unit, NA not available