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Resveratrol treatment prevented neuronal apoptosis by activating the silent information regulator 1 (SIRT1)/RhoA pathway in the hippocampus of adult rats. (A) Representative Western blotting bands. (B-D) Densitometric quantification of SIRT1, RhoA, cleaved Caspase-3, and Bcl2 based on their ratios to β-actin. Data are shown as the mean ± standard deviation (n = 6, per group one-way repeated measures ANOVA, Tukey’s post hoc test). *p < 0.05; **p < 0.01.
