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. 2022 Jan 21;50(3):1335–1350. doi: 10.1093/nar/gkac024

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© The Author(s) 2022. Published by Oxford University Press on behalf of Nucleic Acids Research.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 7. — Effect of variants on CASP8 and MAN2C1 transcripts. (A) Variant-gene network of the two variants rs3769821 and rs1830298. (B) Effect of the variant rs3769821 on the transcript level of CASP8 gene under the additive model. (C) Effect of the variant rs1830298 on the transcript level of CASP8 gene under the additive model. (D) Combined effect of the two variants rs3769821 (first pair of nucleotides in the label) and rs1830298 (second pair) on CASP8. (E) Variant-gene network of the two variants rs59356490 and rs8027365. (F) Effect of the variant rs59356490 on the transcript level of MAN2C1 under the additive model. (G) Effect of the variant rs8027365 on the transcript level of MAN2C1 under the additive model. (H) Combined effect of the two variants rs59356490 (first pair of nucleotides in the label) and rs8027365 (second pair) on MAN2C1.