表 1.
各型FD患者的临床及随访资料
Clinical characteristics and follow-up data of the different types of FD patients
| Items | MFD (n=43) | PFD (n=32) | MAS (n=7) | CFD (n=23) | Total (n=105) |
| Data are presented as x±s, n (%), or M (P25, P75). FD, fibrous dysplasia; MFD, monostotic fibrous dysplasia; PFD, polyostotic fibrous dysplasia; MAS, McCune-Albright syndrome; CFD, craniofacial fibrous dysplasia; ALP, alkaline phosphatase; NA, not available. | |||||
| Onset age/years | 15.00 (13.00, 30.00) | 9.50 (5.50, 12.75) | 8.57±2.37 | 10.00 (6.00, 14.00) | 12.00 (8.00, 17.00) |
| Onset age group/years | |||||
| ≤10 | 7 (16.28) | 21 (65.63) | 5 (71.43) | 13 (56.52) | 46 (43.81) |
| 11-20 | 23 (53.49) | 7 (21.88) | 2 (28.57) | 7 (30.43) | 39 (37.14) |
| 21-30 | 4 (9.30) | 2 (6.25) | 0 (0) | 2 (8.70) | 8 (7.62) |
| 31-40 | 6 (13.95) | 1 (3.13) | 0 (0) | 1 (4.35) | 8 (7.62) |
| 41-50 | 1 (2.32) | 1 (3.13) | 0 (0) | 0 (0) | 2 (1.90) |
| 51-60 | 2 (4.65) | 0 (0) | 0 (0) | 0 (0) | 2 (1.90) |
| Gender | |||||
| Male | 20 (46.51) | 12 (37.50) | 1 (14.29) | 13 (56.52) | 46 (43.81) |
| Female | 23 (53.49) | 20 (62.50) | 6 (85.71) | 10 (43.48) | 59 (56.19) |
| Clinical sign | |||||
| Facial deformity | 39 (90.70) | 32 (100.00) | 7 (100.00) | 23 (100.00) | 101 (96.19) |
| Pain | 8 (18.60) | 2 (6.25) | 1 (14.29) | 1 (4.35) | 12 (11.43) |
| Treatment | |||||
| Conservative surgery | 41 (95.35) | 30 (93.75) | 6 (85.71) | 21 (91.30) | 98 (93.33) |
| Radical surgery with reconstruction | 2 (4.65) | 2 (6.25) | 1 (14.29) | 2 (8.70) | 7 (6.67) |
| Number of conservative operations | 1.0 (1.0, 1.5) | 2.0 (1.0, 3.0) | 2.0 (1.0, 3.5) | 1.0 (1.0, 1.5) | 1.0 (1.0, 2.0) |
| Course | 8.78±7.86 | 17.09±10.27 | 18.86±9.56 | 10.39±6.77 | 12.34±9.34 |
| Serum ALP concentration | |||||
| Elevation | 5 (11.63) | 22 (68.75) | 6 (85.71) | 11 (47.83) | 44 (41.90) |
| Non-elevation | 36 (83.72) | 10 (31.25) | 1 (14.29) | 11 (47.83) | 58 (55.24) |
| NA | 2 (4.65) | 0 (0) | 0 (0) | 1 (4.35) | 3 (2.86) |
| Follow-up | |||||
| No regrowth | 28 (65.12) | 18 (56.25) | 3 (42.86) | 16 (69.57) | 65 (61.90) |
| Slow regrowth | 3 (6.98) | 3 (9.38) | 1 (14.29) | 1 (4.35) | 8 (7.62) |
| Marked regrowth | 2 (4.65) | 3 (9.38) | 0 (0) | 2 (8.70) | 7 (6.67) |
| Death | 0 (0) | 0 (0) | 1 (14.29) | 0 (0) | 1 (0.95) |
| Loss to follow-up | 10 (23.26) | 8 (25.00) | 2 (28.57) | 4 (17.39) | 24 (22.86) |