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. 2021 Dec 17;54(1):54–61. [Article in Chinese] doi: 10.19723/j.issn.1671-167X.2022.01.009

表 1.

各型FD患者的临床及随访资料

Clinical characteristics and follow-up data of the different types of FD patients

Items MFD (n=43) PFD (n=32) MAS (n=7) CFD (n=23) Total (n=105)
  Data are presented as x±s, n (%), or M (P25, P75). FD, fibrous dysplasia; MFD, monostotic fibrous dysplasia; PFD, polyostotic fibrous dysplasia; MAS, McCune-Albright syndrome; CFD, craniofacial fibrous dysplasia; ALP, alkaline phosphatase; NA, not available.
Onset age/years 15.00 (13.00, 30.00) 9.50 (5.50, 12.75) 8.57±2.37 10.00 (6.00, 14.00) 12.00 (8.00, 17.00)
Onset age group/years
  ≤10 7 (16.28) 21 (65.63) 5 (71.43) 13 (56.52) 46 (43.81)
  11-20 23 (53.49) 7 (21.88) 2 (28.57) 7 (30.43) 39 (37.14)
  21-30 4 (9.30) 2 (6.25) 0 (0) 2 (8.70) 8 (7.62)
  31-40 6 (13.95) 1 (3.13) 0 (0) 1 (4.35) 8 (7.62)
  41-50 1 (2.32) 1 (3.13) 0 (0) 0 (0) 2 (1.90)
  51-60 2 (4.65) 0 (0) 0 (0) 0 (0) 2 (1.90)
Gender
  Male 20 (46.51) 12 (37.50) 1 (14.29) 13 (56.52) 46 (43.81)
  Female 23 (53.49) 20 (62.50) 6 (85.71) 10 (43.48) 59 (56.19)
Clinical sign
  Facial deformity 39 (90.70) 32 (100.00) 7 (100.00) 23 (100.00) 101 (96.19)
  Pain 8 (18.60) 2 (6.25) 1 (14.29) 1 (4.35) 12 (11.43)
Treatment
  Conservative surgery 41 (95.35) 30 (93.75) 6 (85.71) 21 (91.30) 98 (93.33)
  Radical surgery with reconstruction 2 (4.65) 2 (6.25) 1 (14.29) 2 (8.70) 7 (6.67)
  Number of conservative operations 1.0 (1.0, 1.5) 2.0 (1.0, 3.0) 2.0 (1.0, 3.5) 1.0 (1.0, 1.5) 1.0 (1.0, 2.0)
  Course 8.78±7.86 17.09±10.27 18.86±9.56 10.39±6.77 12.34±9.34
Serum ALP concentration
  Elevation 5 (11.63) 22 (68.75) 6 (85.71) 11 (47.83) 44 (41.90)
  Non-elevation 36 (83.72) 10 (31.25) 1 (14.29) 11 (47.83) 58 (55.24)
  NA 2 (4.65) 0 (0) 0 (0) 1 (4.35) 3 (2.86)
Follow-up
  No regrowth 28 (65.12) 18 (56.25) 3 (42.86) 16 (69.57) 65 (61.90)
  Slow regrowth 3 (6.98) 3 (9.38) 1 (14.29) 1 (4.35) 8 (7.62)
  Marked regrowth 2 (4.65) 3 (9.38) 0 (0) 2 (8.70) 7 (6.67)
  Death 0 (0) 0 (0) 1 (14.29) 0 (0) 1 (0.95)
  Loss to follow-up 10 (23.26) 8 (25.00) 2 (28.57) 4 (17.39) 24 (22.86)