Table 1.

Frequency of NTRK fusions in patients with cancer^16–18.

Histology	Frequency, %
Overall	0.28
Secretory breast carcinoma	92.87
Infantile fibrosarcoma	90.56
Secretory salivary gland cancer	79.68
Pleomorphic adenoma	50.47
Papillary thyroid carcinoma, pediatric	25.93
Differentiated thyroid cancer, pediatric	22.22
Inflammatory myofibroblastic tumor	17.7
Salivary gland carcinoma	5.08–5.29
Thyroid cancer	2.22–2.28
Sarcoma	0.68–1.17
Glioblastoma multiforme	0.62
Glioma/neuroepithelial tumor	0.55
Appendiceal adenocarcinoma	0.48–0.57
Melanoma	0.36–0.54
Biliary tract cancer	0.36
Cervical carcinoma	0.36
Colorectal cancer	0.26–0.35
Unknown primary	0.31
Neuroendocrine tumors	0.26–0.31
Pancreatic cancer	0.30–0.34
Cholangiocarcinoma	0.25
Lung adenocarcinoma	0.16–0.23
Invasive breast carcinomaa	0.08–0.13

NOS = not otherwise specified

^aExcludes secretory breast cancer.