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. 2021 Sep 20;35(3):427–437. doi: 10.1038/s41379-021-00918-3

Fig. 2. Identification of unusual MMR-D tumors after IHC and MSI review: *11/13 cases were clearly assigned to one category of loss of MMR proteins and 2/11 cases remained indeterminate for at least one MMR protein (PMS2).

Fig. 2

**: for one case, initial IHC was performed on biopsy with normal expression of MMR proteins but with an isolated loss of PMS2 on the surgical sample, and for the other case, initial IHC was performed on a polyp with normal expression of MMR protein but with PMS2/MLH1 loss on invasive carcinoma.