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. 2021 Jul 9;13(1):185–194. doi: 10.1007/s41999-021-00533-0

Table 2.

Associations of daily opioid use with sociodemographic and clinical characteristics among aged home care clients

Characteristics Unadjusted Multivariable model 1 Multivariable model 2
OR (95% CI) Adjusted OR (95% CI) Adjusted OR (95% CI)
Age (year) 1.00 (0.99–1.02) 0.99 (0.97–1.01) 0.99 (0.97–1.01)
Gender, female 1.50 (1.11–2.04) 1.20 (0.85–1.68) 0.99 (0.69–1.42)
Disability in ADLs (≥ 1) 1.41 (1.08–1.84) 1.20 (0.86–1.67) 1.14 (0.80–1.61)
Performance in IADLs
 0–7 1 1 1
 8–14 1.56 (1.14–2.11) 1.63 (1.17–2.25) 1.62 (1.15–2.28)
 15–21 1.49 (1.06–2.07) 1.68 (1.10–2.56) 1.89 (1.21–2.96)
Unstable health state (CHESS ≥ 3) 1.47 (1.03–2.11) 1.16 (0.78–1.74) 0.84 (0.55–1.28)
Depressive symptoms (DRS ≥ 3) 1.97 (1.46–2.65) 2.05 (1.48–2.85) 1.25 (0.88–1.78)
Cognitive impairment (CPS ≥ 2) 0.55 (0.43–0.71) 0.43 (0.32–0.58) 0.54 (0.40–0.74)
Chronic conditions
 Arthritis 1.70 (1.17–2.47) 1.56 (1.05–2.33) 1.35 (0.89–2.07)
 Cancer (within previous 5 years) 1.51 (1.01–2.25) 1.73 (1.13–2.64) 1.59 (1.02–2.49)
 Cardiac disease 1.18 (0.92–1.51) 1.14 (0.87–1.50) 1.09 (0.82–1.45)
 Chronic renal failure 1.13 (0.74–1.72) 1.02 (0.66–1.60) 0.93 (0.58–1.48)
 Diabetes 1.05 (0.80–1.37) 1.17 (0.88–1.57) 1.28 (0.94–1.73)
 History of any fracture affecting the present health status 1.82 (1.22–2.71) 1.46 (0.96–2.23) 1.23 (0.79–1.91)
 History of stroke 0.68 (0.42–1.12) 0.69 (0.41–1.16) 0.73 (0.42–1.26)
 Osteoporosis 2.80 (2.14–3.66) 2.60 (1.95–3.49) 2.29 (1.68–3.12)
 Parkinson’s disease 2.06 (1.13–3.74) 1.93 (1.01–3.69) 1.98 (0.99–3.97)
 Peripheral arterial disease or venous insufficiency 1.14 (0.77–1.69) 0.94 (0.62–1.44) 0.80 (0.52–1.24)
 Pressure ulcer 2.36 (1.47–3.77) 2.00 (1.20–3.33) 1.40 (0.81–2.43)
Pain scale
 No 1 1
 Less than daily 3.89 (2.32–6.52) 3.42 (2.02–5.78)
 Daily, mild to moderate 8.17 (5.07–13.17) 6.67 (4.08–10.89)
 Daily, severe 25.47 (15.42–42.07) 20.15 (11.87–34.22)

Model 1 adjusted for all factors mentioned above except the Pain scale (Hosmer–Lemeshow p value 0.252). Model 2 adjusted for all factors mentioned above (Hosmer–Lemeshow p-value 0.470)