Table 2.

Association between sex, child age, and adiposity, and log transformed cytokine levels under unstimulated and stimulated conditions.

	Stimulation Conditions	Sex	Log10(Age, yr)	BMI z-score	Log10(% Fat Mass)
		Compared to Female	Adjusted for Sex		Adjusted for Age and Sex
IL-1β	Unstimulated	-0.00 (-0.16, 0.15)	0.30 (0.02, 0.57)	0.07 (-0.01, 0.16)	0.01 (-0.01, 0.04)
	LPS	0.00 (-0.08, 0.08)	-0.18 (-0.33, -0.04)	-0.03 (-0.07, 0.02)	-0.01 (-0.02, 0.01)
	PGN	0.07 (-0.03, 0.18)	-0.06 (-0.25, 0.13)	-0.00 (-0.03, 0.01)	-0.00 (-0.02, 0.01)
IL-6	Unstimulated	-0.07 (-0.22, 0.08)	0.18 (-0.09, 0.44)	0.01 (-0.07, 0.09)	0.00 (-0.02, 0.03)
	LPS	0.02 (-0.03, 0.08)	-0.04 (-0.15, 0.06)	0.01 (-0.02, 0.04)	0.01 (-0.00, 0.02)
	PGN	0.06 (0.00, 0.12)	-0.07 (-0.17, 0.04)	0.02 (-0.02, 0.05)	0.00 (-0.01, 0.01)
TNFα	Unstimulated	-0.01 (-0.09, 0.07)	0.09 (-0.05, 0.23)	0.01 (-0.04, 0.05)	0.00 (-0.01, 0.02)
	LPS	0.05 (-0.01, 0.11)	0.00 (-0.11, 0.11)	-0.01 (-0.04, 0.02)	0.00 (-0.01, 0.01)
	PGN	0.06 (-0.01, 0.12)	0.00 (-0.12, 0.12)	-0.02 (-0.05, 0.02)	-0.01 (-0.02, 0.01)
IL-12p70	Unstimulated	0.02 (-0.01, 0.05)	0.04 (-0.01, 0.09)	0.00 (-0.01, 0.02)	0.00 (-0.00, 0.01)
	LPS	0.05 (0.00, 0.10)	-0.02 (0.12, 0.07)	-0.01 (-0.04, 0.02)	0.00 (-0.01, 0.01)
	PGN	0.03 (0.00, 0.06)	-0.00 (-0.05, 0.05)	-0.01 (-0.02, 0.01)	-0.00 (-0.01, 0.00)
IL-1RA	Unstimulated	0.04 (-0.05, 0.14)	0.13 (-0.02, 0.30)	0.03 (-0.01, 0.08)	0.00 (-0.01, 0.02)
	LPS	0.05 (-0.01, 0.10)	-0.04 (-0.14, 0.07)	0.02 (-0.01, 0.05)	0.01 (-0.00, 0.02)
	PGN	0.07 (0.01, 0.13)	-0.01 (-0.12, 0.10)	0.01 (-0.02, 0.04)	-0.00 (-0.01, 0.01)
IL-10	Unstimulated	0.02 (-0.05, 0.08)	0.04 (-0.08, 0.16)	0.02 (-0.02, 0.06)	-0.00 (-0.01, 0.01)
	LPS	0.07 (0.00, 0.14)	0.04 (-0.08, 0.16)	0.02 (-0.02, 0.05)	0.00 (-0.01, 0.01)
	PGN	0.09 (0.01, 0.17)	-0.13 (-0.27, 0.00)	-0.01 (-0.05, 0.03)	0.00 (-0.01, 0.01)

Linear regression analysis. Beta coefficients (units=Log₁₀(pg/ml of cytokine) per variable) with 95% confidence interval (CI). Those in bold indicate a p value <0.05