Fig. 6.

Details of the packing of the folded Nt₂₀ region in Tre_A (A) and Tre_D (B) with the rest of the protein. The structures correspond to representatives of the conformational ensemble extracted from the ST MD trajectory. Relevant amino acid side chains are shown in CPK representation and labeled. Nt residues are colored following the same code as in Fig. 3. Figure generated with PyMOL 2.5.0 (Schrödinger LLC; https://pymol.org/). (For interpretation of the references to colour in this figure legend, the reader is referred to the web version of this article.)