Table 2.
ROC analysis of diagnostic accuracy of semi-quantitative imaging markers
| Threshold value* | Sens | Spec | pLR | nLR | AUC | |
|---|---|---|---|---|---|---|
| SUVmax | 5.82 | 0.70 | 0.92 | 8.26 | 0.33 | 0.88 (0.75, 1.00) |
| SUVpeak | 5.00 | 0.70 | 0.97 | 20.65 | 0.31 | 0.88 (0.75, 1.00) |
| SULmax | 8.83 | 0.67 | 0.90 | 6.56 | 0.37 | 0.86 (0.72, 0.99) |
| SULpeak | 7.58 | 0.67 | 0.98 | 39.33 | 0.34 | 0.86 (0.72, 1.00) |
| Delayed SUVmax | 2.53 | 1.00 | 0.56 | 2.29 | 0.00 | 0.81 (0.53, 1.09) |
| Delayed SUVpeak | 2.08 | 1.00 | 0.63 | 2.67 | 0.00 | 0.85 (0.61, 1.10) |
| Delayed SULmax | 3.42 | 1.00 | 0.50 | 2.00 | 0.00 | 0.69 (0.28, 1.10) |
| Delayed SULpeak | 2.81 | 1.00 | 0.63 | 2.67 | 0.00 | 0.78 (0.44, 1.12) |
| TLmax | 1.66 | 0.90 | 0.86 | 6.53 | 0.12 | 0.92 (0.84, 1.01) |
| TLmean | 2.31 | 0.90 | 0.79 | 4.35 | 0.13 | 0.91 (0.81, 1.00) |
Table showing ROC analysis of diagnostic accuracy of semi-quantitative imaging markers. *Optimal threshold obtained through Youden’s method. AUC area under the receiver operating curve; nLR negative likelihood ratio; pLR positive likelihood ratio; sens sensitivity; spec specificity; SUV standard uptake value; SUL standard uptake value adjusted for lean body mass; TLmax tumor-to-liver maximal ratio; TLmean tumor-to-liver mean ratio