TABLE 1.
Resistance rates to carbapenems and other antipseudomonal drugs among P. aeruginosa isolates recovered in AHEPA University Hospital
| Antibiotic(s) | No. (%) of resistanta isolates in:
|
|||
|---|---|---|---|---|
| 1996 | 1997 | 1998 | Total | |
| Imipenem only | 19 (4.2) | 11 (2.4) | 8 (2.2) | 38 (3.0) |
| Meropenem only | 5 (1.1) | 3 (0.7) | 3 (0.8) | 11 (0.9) |
| Imipenem and meropenem | 83 (18.5) | 94 (20.5) | 34 (9.2) | 211 (16.5) |
| Ceftazidime | 121 (27.0) | 138 (30.1) | 86 (23.3) | 345 (27.0) |
| Aztreonam | 97 (21.7) | 136 (29.6) | 78 (21.1) | 311 (24.4) |
| Ciprofloxacin | 182 (40.6) | 163 (35.5) | 101 (27.4) | 446 (35.0) |
| Gentamicin | 115 (25.7) | 124 (27.0) | 79 (21.4) | 318 (24.9) |
| Amikacin | 91 (20.3) | 100 (21.8) | 61 (16.5) | 252 (19.7) |
| Piperacillin-tazobactamb | 122 (27.2) | 141 (30.7) | 79 (21.4) | 342 (26.8) |
| Total isolates | 448 | 459 | 369 | 1,276 |
a
Resistance was defined in accordance with NCCLS interpretive criteria.
b
Tazobactam tested at a fixed concentration of 4 μg/ml.