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. 2022 Feb 22;8:19. doi: 10.1038/s41421-022-00379-1

Fig. 5. Ordered pore loops in p97 double hexamer (DH).

Fig. 5

Cryo-EM density of the pore loops in D1 and D2 rings of p97 SH conformer I (a) and DH conformer II (b). The contour levels for the SH and DH are set at 0.010 (2σ) and 0.020 (5σ), respectively. c Surface diagram of SH I (left) and one hexamer of DH II (right) in bottom view. The N, D1, and D2 domains are colored green, cyan, and blue, respectively. ɑ9 and the D2 pore loop 2 are colored yellow. The diameters of the central pore and the D2 ring are indicated. d Superimposition of two adjacent protomers of SH I and DH II. Structural elements exhibiting conformational changes are boxed with red dashed lines.